Protein-Protein Interactions of Proteins from the ESAT-6 Family of Mycobacterium tuberculosis

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Protein-protein interactions of proteins from the ESAT-6 family of Mycobacterium tuberculosis.

In the present study, we demonstrate that, in analogy with the genes encoding ESAT-6 and CFP-10, the genes rv0287 and rv0288 from the ESAT-6 gene family are cotranscribed. Using Western-Western blotting and protein-print overlay methodologies, we demonstrate that ESAT-6 and CFP-10, as well as the protein pair Rv0288/Rv0287, interact pairwise in a highly specific way. Most notably, the ESAT-6 pr...

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ژورنال

عنوان ژورنال: Journal of Bacteriology

سال: 2004

ISSN: 0021-9193,1098-5530

DOI: 10.1128/jb.186.8.2487-2491.2004